Xarelto (rivaroxaban) is an anticoagulant. Side effects are mainly related to bleeding, since the medicine decreases your blood’s ability to clot. Side effects can vary by dose and individual factors.
Common side effects (these happen to some people):
- Bleeding or bruising more easily than normal
- Nosebleeds or bleeding gums
- heavier or longer menstrual bleeding
- blood in urine or stool (a sign of possible internal bleeding)
- Headache, dizziness
- Upset stomach, nausea
- Back pain or muscle aches
- Anemia (rarely)
Serious but less common side effects (seek medical help promptly):
- Major or uncontrolled bleeding (for example, prolonged bleeding from cuts, vomiting blood, coughing up blood, unusually heavy menstrual bleeding, blood in stool or urine, very dark or tarry stools)
- Signs of internal bleeding such as severe abdominal pain, fainting, or confusion
- Signs of a severe allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing
- Signs of possible liver problems: yellowing of the skin or eyes, dark urine, severe stomach/upper abdominal pain
Important safety points:
- Do not take Xarelto with other blood thinners or more NSAIDs/antiplatelet drugs unless your clinician approves, since this increases bleeding risk.
- Tell your doctor if you have kidney or liver problems, as dosing and safety can be affected.
- Spinal/epidural procedures (like certain anesthesia) carry a risk of a spinal/epidural hematoma with rivaroxaban; discuss timing with your doctor if you’re getting such procedures.
- Not every patient should use Xarelto (e.g., certain valve problems, pregnancy, or breastfeeding—discuss with your doctor).
What to do if you’re concerned about side effects:
- If you notice any signs of major bleeding or an allergic reaction, seek urgent medical care.
- For non-urgent side effects that bother you or don’t go away, contact your clinician to decide whether to adjust your dose or switch medications.
If you’d like, tell me your indication (e.g., atrial fibrillation, DVT/PE treatment, post-surgical prophylaxis) and your dose, and I can share more specific side effect information and what to watch for. This doesn’t replace medical advice—please consult your healthcare provider for guidance tailored to you.