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Are you experiencing any fatigue as a side effect of Lipitor? Fatigue shows up in clinical reports as a possible side effect of atorvastatin, the active ingredient in Lipitor. Some patients report feeling tired after starting treatment, but many also have conditions such as diabetes or hypothyroidism that can produce the same feeling. Why do some patients report fatigue on Lipitor? Muscle breakdown or mild myalgia can leave people feeling tired even when pain is not dominant. Laboratory tests show that atorvastatin may reduce coenzyme Q10 levels in muscles, a change that has been linked to fatigue in a small percentage of users.
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