Zyprexa Zydis (olanzapine) is the brand‑name, rapid‑disintegration film formulation of olanzapine. Because it’s a brand product, its price can be higher than generic olanzapine tablets, but the exact cost varies widely depending on a few key factors:
| Factor | How it affects cost |
|--------|---------------------|
| Dosage strength | Higher milligram strengths (e.g., 15 mg) are more expensive per tablet. |
| Quantity | Buying a 30‑tablet bottle (typical month’s supply) will cost more than a 10‑tablet bottle. |
| Insurance coverage | Some plans cover Zyprexa Zydis at a lower copay or even fully. Others may not cover it and you pay full price. |
| Pharmacy discount cards / patient assistance | Programs offered by the manufacturer or third‑party discount cards can lower the out‑of‑pocket cost. |
| Region | Prices can differ by state or city due to local pharmacy pricing and formulary decisions. |
Rough price ranges (U.S., 2026)
| Strength | 30‑tablet bottle (typical monthly supply) | 10‑tablet bottle |
|----------|-------------------------------------------|------------------|
| 5 mg | $250–$350 | $80–$120 |
| 10 mg | $500–$700 | $170–$250 |
| 15 mg | $750–$1,000 | $260–$360 |
Note: These are average retail prices and can fluctuate. If you have insurance, your copay could be as low as $0–$30 per month, depending on the plan.
What can you do to find the best price?
1. Check your insurance formulary – Call your pharmacy benefits manager or log into your health plan portal.
2. Ask your prescriber – They can sometimes switch you to a lower‑cost generic if clinically appropriate.
3. Use discount programs –
* The manufacturer often offers a savings card.
* Generic olanzapine (without Zydis) is available at a lower cost—some plans cover it at a reduced copay.
* Third‑party discount cards (e.g., GoodRx, ScriptSave) can lower retail prices by 10–50 %.
4. Compare pharmacies – Prices can vary between chain pharmacies, independent stores, and online retailers.
5. Patient assistance – If you’re uninsured or underinsured, contact the Eli Lilly Patient Assistance Program (the manufacturer of Zyprexa). They may offer a program for qualifying patients.
Quick tip
If your insurance does not cover Zyprexa Zydis, you might consider generic olanzapine. The generic tablets are chemically identical and generally cost 1/5 to 1/10 of the brand price, but the “Zydis” rapid‑disintegration feature is unique to the brand. Discuss with your clinician whether the faster onset of action is necessary for you.
---
Bottom line: Zyprexa Zydis can cost anywhere from $250 to $1,000 for a month’s supply at retail, but most patients pay far less—often $0–$50 per month—once insurance, discounts, or generic substitutions are considered. For the exact amount you’ll owe, check your insurance plan’s formulary or consult your pharmacist.