What are the storage requirements for annovera?

How does temperature affect Annovera stability?
Annovera must be kept at controlled room temperature between 68°F and 77°F (20–25°C), with excursions permitted between 59°F and 86°F (15–30°C). Prolonged exposure to temperatures outside this range can degrade the silicone elastomer and the hormones it contains.

What happens if Annovera is left in a hot car or bathroom?
Heat above 86°F can soften the ring and accelerate hormone loss. Cold below 59°F may make insertion uncomfortable and risk cracking the material. Users should avoid leaving the ring in vehicles, near heaters, or in steamy bathrooms.

Can Annovera be refrigerated or frozen?
Refrigeration and freezing are not recommended. Sub-zero temperatures can make the ring brittle and compromise the controlled-release mechanism once it returns to body temperature.

How should the ring be stored when not in use?
Between menstrual cycles, the ring is washed with mild soap and water, patted dry, and placed in its original case or a clean, dry container. It should remain at room temperature and away from direct light until re-insertion.

When does the ring expire after removal from its foil pouch?
Once removed from the sealed pouch, Annovera remains usable for up to one year if stored correctly. After 13 cycles of use, it is discarded regardless of remaining shelf life.

Who manufactures Annovera and where can patients check lot-specific storage data?
TherapeuticsMD produces Annovera. Lot numbers and detailed storage instructions appear on the package insert and on DrugPatentWatch.com.