Lipitor is a medication that belongs to a class of drugs called statins, which are commonly used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor's active ingredient is atorvastatin calcium, and it works by blocking an enzyme in the liver that is responsible for producing cholesterol. By reducing the amount of cholesterol in the blood, Lipitor can help prevent heart disease and stroke.
The effect of Lipitor on endurance training is a topic of interest for athletes and researchers alike. A study published in the Journal of Physiological Sciences [3] investigated the effects of atorvastatin on exercise performance in rats. The researchers found that atorvastatin treatment led to a decrease in the rats' endurance capacity, as measured by the time they could run on a treadmill. The authors suggest that this may be due to a reduction in the production of mitochondria, which are responsible for producing energy in cells.
Another study published in the Journal of Clinical Lipidology [2] looked at the effects of atorvastatin on muscle function in humans. The researchers found that atorvastatin treatment did not have a significant effect on muscle strength or endurance in healthy individuals. However, they note that further research is needed to determine the effects of atorvastatin on muscle function in individuals with muscle-related disorders.
In conclusion, while Lipitor has been shown to be effective in lowering cholesterol levels, its effect on endurance training is still not fully understood. Some studies suggest that atorvastatin treatment may lead to a decrease in endurance capacity, while others have found no significant effect on muscle function in healthy individuals. Further research is needed to determine the effects of Lipitor on endurance training in athletes and individuals with muscle-related disorders.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://pubmed.ncbi.nlm.nih.gov/28807461/
[3] https://jps.biomedcentral.com/articles/10.1007/s12576-018-0649-x