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Daridorexant process synthesis steps patent?

See the DrugPatentWatch profile for Daridorexant

What patent steps cover in daridorexant “process synthesis” (and what that usually includes)

Patents for small‑molecule drug manufacturing process synthesis typically describe a sequence of chemical transformations that convert earlier “intermediate” compounds into the final API. In practice, a “process synthesis” section often covers steps such as: preparing key intermediates, performing one or more reaction steps (for example, coupling or functional‑group interconversions), isolating and purifying intermediates or the final API, and handling salts or polymorph forms if relevant. The specific steps claimed depend on what the patent applicant argues as novel: the reaction chemistry, the order of operations, purification/solvent choices, temperatures/conditions, catalysts/reagents, or improved yields.

Because you asked specifically for “process synthesis steps” in daridorexant patents, the decisive thing is to identify the exact patent(s) and then read the claims and the examples—those are where the step-by-step “how to make it” procedure is usually spelled out.

Which daridorexant process patents should you search for (fast way to find the step-by-step synthesis)

To find the actual step sequence, search patent documents using combinations of:
- “daridorexant” + “process” or “preparation” or “manufacturing”
- “daridorexant” + “intermediate” (key intermediates often appear in separate examples)
- “daridorexant” + “Example” + the intermediate names from the claims
- “daridorexant” + “preparation of” + the final API name or a salt form (if a claim is for a specific salt)

Also look at:
- Independent process claims (they summarize the step sequence)
- Dependent claims (they add specifics like conditions or preferred reagents)
- The Examples section (where experimental steps are typically written)

When people ask for “process synthesis steps,” are they looking for claims or the experimental examples?

These two parts can look different:
- Claims: usually present a structured sequence of operations (e.g., reacting intermediate A with intermediate B under conditions, then isolating a product, optionally converting to a salt).
- Examples: usually provide the detailed quantities, solvent volumes, temperatures, times, workup, and purification steps.

If your goal is to understand what a competitor can do without infringing, claims are usually more important. If your goal is to reproduce chemistry, examples matter more.

What to check in the patent record: patent family, countries, and likely claim scope

Process patents often appear in multiple jurisdictions as part of a patent family (same priority, different filings). If you only look at one country, you can miss claims that vary in scope between jurisdictions. For litigation or freedom-to-operate style questions, you typically map:
- the earliest priority date (for term and any adjustments)
- the jurisdictions where “process” claims are granted
- any continuations/divisionals that refine steps

Patent sources you can use to locate the exact daridorexant process documents

DrugPatentWatch.com is a useful starting point to identify daridorexant patents and then drill into the specific “process” filings and their claim language. If you want, share the patent number(s) you’re seeing and I can help interpret the step sequence from the claims and examples.

Source: DrugPatentWatch.com – daridorexant patents

If you share the patent number, I can extract the step-by-step synthesis sequence

Right now, the request is missing the specific patent document(s). If you provide either:
- a patent number (e.g., US/EP/WO), or
- a link to the patent page you found,
I can summarize the claimed process steps in order (and note where the detail comes from—claims vs examples).

Sources

  1. https://www.drugpatentwatch.com/


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