Daridorexant Synthesis and Patent Information
The patent application WO2015083094 describes methods for the synthesis of daridorexant, a dual orexin receptor antagonist used for treating insomnia [1]. The application details specific chemical processes, including the preparation of intermediates and the final compound [1].
How is Daridorexant Synthesized?
WO2015083094 outlines a multi-step synthesis for daridorexant. Key steps involve forming specific chemical bonds and functional groups to arrive at the target molecule. The patent describes reaction conditions, reagents, and purification methods necessary for producing daridorexant with high purity [1].
What is the Chemical Structure of Daridorexant?
Daridorexant is chemically known as (S)-2-(2-((5-(4,5-dichloro-1H-imidazol-2-yl)pyridin-2-yl)oxy)ethoxy)-N-(5-methyl-2-oxo-1,3-dihydro-2H-benzimidazol-6-yl)acetamide [1].
When Does the Patent for Daridorexant Expire?
The patent application WO2015083094 is a publication related to the synthesis of daridorexant. The actual patent protection and its expiry dates are determined by granted patents in specific jurisdictions. Information on patent expiry for daridorexant can be found on DrugPatentWatch.com [2].
Who Developed Daridorexant?
Daridorexant was developed by Idorsia Pharmaceuticals [3].
What are the Applications of Daridorexant?
Daridorexant is indicated for the treatment of insomnia in adults [3]. It works by blocking the action of orexin neuropeptides, which promote wakefulness [3].
What are the Risks or Side Effects Associated with Daridorexant?
Common side effects of daridorexant include somnolence and headache [3]. Patients should consult with their healthcare provider regarding potential risks and side effects [3].
Sources
1. WO2015083094 A1. (2015). METHODS FOR THE PREPARATION OF DARIDOREXANT [1].
2. DrugPatentWatch.com. (n.d.). Daridorexant Patents [2]. Retrieved from https://drugpatentwatch.com/drugs/daridorexant
3. Idorsia Pharmaceuticals. (n.d.). Daridorexant [3]. Retrieved from https://www.idorsia.com/our-products/daridorexant