Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. It is important to be cautious when taking natural remedies with Lipitor, as some remedies may interact with the medication and cause adverse effects.

According to the NHS [2], St John's wort, a natural remedy commonly used to treat depression, anxiety, and sleep disorders, should be avoided with Lipitor. St John's wort may increase the breakdown of Lipitor in the liver, reducing its effectiveness and potentially leading to an increased risk of side effects.

Similarly, the Mayo Clinic [3] advises against taking red yeast rice, a natural remedy used to lower cholesterol levels, with Lipitor. Red yeast rice contains a substance that is similar to the active ingredient in Lipitor and taking both together may increase the risk of side effects, such as muscle pain and liver damage.

Other natural remedies that may interact with Lipitor include grapefruit juice, which can increase the levels of Lipitor in the blood and increase the risk of side effects [2]. Additionally, coenzyme Q10, a natural supplement used to support heart health, may decrease the effectiveness of Lipitor [3].

It is important to speak with a healthcare provider before taking any natural remedies with Lipitor to ensure they are safe and effective. They may recommend alternative remedies or adjust the dosage of Lipitor to minimize the risk of interactions.

Sources:
[2] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/
[3] https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/herbal-supplements/art-20046488