See the DrugPatentWatch profile for Phisohex
The active ingredient in Phisohex is hexachlorophene [1].
What is Hexachlorophene used for?
Hexachlorophene is an antiseptic and disinfectant [2]. It is primarily used as a topical agent to reduce bacteria on the skin [1]. This is often employed in healthcare settings to help prevent the spread of infections [3].
How does Hexachlorophene work?
Hexachlorophene functions by disrupting the cell membranes of bacteria, which leads to their death [4]. It has a broad spectrum of activity against gram-positive bacteria, particularly Staphylococcus species [3].
Are there safety concerns with Hexachlorophene?
Yes, hexachlorophene has had significant safety concerns associated with its use. In the past, it was more widely used in consumer products like soaps and cosmetics. However, studies revealed that hexachlorophene could be absorbed through the skin and cause neurological damage, particularly in infants [5]. This led to severe restrictions on its use [6]. It is now generally restricted to prescription topical use by healthcare professionals [3][5].
Where can I find information on drug patents?
Information regarding drug patents, including those related to active ingredients like hexachlorophene and their associated formulations, can be found on resources like DrugPatentWatch.com [7].