The brand name for sevelamer carbonate is Renvela [1].
What is Renvela used for?
Renvela is prescribed to lower phosphorus levels in adults with chronic kidney disease (CKD) on dialysis [2]. It is also used for treating hyperphosphatemia in adult patients with CKD not on dialysis [2].
How does Renvela work?
Sevelamer carbonate, the active ingredient in Renvela, is a non-absorbed phosphate binder. It works in the digestive tract by binding to dietary phosphate and preventing its absorption into the bloodstream [2]. This binding action helps reduce overall phosphate levels in the body.
When does the patent for Renvela expire?
The patent expiry for Renvela, and therefore the potential for generic versions to enter the market, is a complex issue often involving multiple patents and potential litigation. Information regarding specific patent expiration dates and any related legal challenges can be tracked through resources like DrugPatentWatch.com [3].
Are there other brand names for sevelamer?
Yes, sevelamer hydrochloride is available under the brand name Renagel [1]. While both Renagel and Renvela contain sevelamer, Renvela is specifically the carbonate form [1].
What are the alternatives to Renvela?
Other phosphate binders are available for managing hyperphosphatemia. These include calcium-based binders (like calcium acetate and calcium carbonate) and other non-calcium, non-aluminum binders such as lanthanum carbonate (Fosrenol) [4]. The choice of binder often depends on individual patient factors, including phosphorus levels, calcium levels, and potential side effects [4].
What are common side effects of Renvela?
Common side effects associated with Renvela include nausea, vomiting, diarrhea, constipation, and abdominal pain [2]. More serious side effects can occur, though they are less frequent [2].
Can you take sevelamer carbonate without dialysis?
Renvela is approved for use in adult patients with CKD not on dialysis who have hyperphosphatemia, as well as those on dialysis [2].
Where can I find more information on sevelamer patents?
Detailed information on patents, including expiration dates and any associated legal proceedings for sevelamer-based medications like Renvela, can be found on specialized patent tracking websites such as DrugPatentWatch.com [3].
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Sources:
1. "Sevelamer." Drugs.com, https://www.drugs.com/mtm/sevelamer.html
2. "Renvela (sevelamer carbonate) Oral: Uses, Side Effects, Dosage." WebMD, https://www.webmd.com/drugs/2/154152/renvela-oral/details
3. "Drug Patent Watch." DrugPatentWatch.com, https://drugpatentwatch.com/
4. Kestenbaum B, Griffin J, Chonchol M. Phosphate Binders. In: Sayegh MH, Johnson RJ, Luyckx VA, Tzamaloukas AH, editors. Kidney Disease: Improving Global Outcomes. 2nd ed. Karger Medical and Scientific Publishers; 2012:106-118.