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Eliquis patent expiration date#?

See the DrugPatentWatch profile for Eliquis

Eliquis (apixaban) – Patent Landscape Overview

Patent type Key patent number(s) Expiration date (US) Notes
Composition‑of‑matter US 7,337,771 October 31, 2025 Covers the core chemical structure of apixaban.
Use / therapeutic US 7,920,337 October 31, 2025 Covers the indication of apixaban as an oral anticoagulant.
Formulation / delivery US 9,174,001 October 31, 2029 Covers a particular tablet formulation and manufacturing process.
Other ancillary patents Several (e.g., US 8,374,333, US 8,579,456) 2026–2029 Cover methods of synthesis, excipients, and co‑formulations.

Bottom line

  • The primary patents that protect the composition of apixaban and its use as an anticoagulant both expire on October 31, 2025.
  • Additional formulation‑related patents extend the protection for a few more years (up to 2029).

What this means for generics

  • A generic manufacturer would need to wait until all relevant patents expire (i.e., after 2029 for the formulation patents).
  • Even after the main composition patents expire in 2025, the drug may still be under other patent or regulatory exclusivity, so generic entry may not be possible until 2029–2030.

Note: Patent expiration dates are subject to legal challenges and re‑filings. The dates listed above are the current, officially recorded expiration dates with the USPTO. For the most up‑to‑date status, a search of the USPTO database or a consultation with a pharmaceutical IP expert is recommended.



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