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What side effects did patients report with Lipitor? Patients taking atorvastatin, the active ingredient in Lipitor, reported muscle pain as one of the most common complaints. Many described mild to moderate pain, weakness, or tenderness in the muscles. Clinical data show rates of myalgia between 1.5% and 5% in large trials, but real-world reports run higher because patients often continue treatment after a complaint. How does muscle pain develop on Lipitor? Muscle pain can appear shortly after starting atorvastatin or after a dose increase. It occurs when statins interfere with the production of CoQ10, a coenzyme essential for energy production in muscle cells. Some patients experience it als<|eos|>
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