See the DrugPatentWatch profile for Cosentyx
Can Cosentyx (secukinumab) cause mood swings?
Cosentyx (secukinumab) is used for conditions like plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. In the information provided here, there is no specific, confirmed link described between Cosentyx and “mood swings” as a named side effect.
That said, mood-related symptoms can happen for many reasons in people with chronic inflammatory diseases, including disease activity, stress, sleep disruption, and other medications. If you notice a new change in mood after starting Cosentyx, it’s worth discussing with your prescriber.
What else could be causing mood changes while taking Cosentyx?
If mood swings started around the time you began Cosentyx, common alternative explanations to ask about include:
- Changes in overall disease activity (pain, fatigue, inflammation)
- Sleep changes due to symptoms
- Stress or anxiety related to the illness or treatment
- Other medications you take (especially corticosteroids, antidepressants, or dose changes)
- Alcohol or substance changes that sometimes track with symptom changes
Your clinician can help determine whether the timing and pattern fits medication effects or other causes.
When should you contact a doctor urgently?
Contact your clinician promptly if mood changes are severe, rapidly worsening, or include any signs of depression or mania such as:
- Thoughts of self-harm or suicide
- Feeling extremely agitated, unable to sleep, or unusually “up”
- Paranoia, hallucinations, or major behavior changes
If you’re in immediate danger, seek emergency care.
How do clinicians handle suspected mood-related side effects from Cosentyx?
A typical approach is:
- Review when mood symptoms began relative to the Cosentyx start or dose timing
- Check for other causes (other meds, recent illness, sleep problems, mental health history)
- Decide whether to continue, pause, or switch therapy based on overall risk/benefit
- Involve mental health care if symptoms suggest a psychiatric condition that needs treatment
Your prescriber can tailor this to your situation and the condition you’re treating.
What details to track so your doctor can assess the cause
When you report mood swings, it helps to include:
- Start date of Cosentyx and start date of mood symptoms
- How often it happens and what the mood changes look like
- Triggers (sleep, pain flares, stress)
- Any other medication changes (including steroids)
- Any prior history of depression, anxiety, bipolar disorder, or similar symptoms
If you tell me your situation, I can help you draft questions for your doctor
If you share: your condition being treated (psoriasis/psoriatic arthritis/ankylosing spondylitis), when you started Cosentyx, and what the mood swings feel like (timing, duration, severity), I can suggest the most relevant questions to ask your prescriber.