Based on the available information, there are some potential interactions and side effects to consider when combining aspirin and Vascepa (icosapent ethyl). According to Drugs.com, there is a moderate interaction between these two medications [${1}]. This interaction could increase the risk of bleeding, especially in the gastrointestinal tract.

Some potential side effects of this combination include:

1. Increased risk of bleeding: Both aspirin and Vascepa can affect platelets, which are responsible for blood clotting. When used together, they might increase the risk of bleeding, particularly in the gastrointestinal tract [${1}].
2. Stomach ulcers or stomach pain: Aspirin can irritate the stomach lining, potentially leading to ulcers or stomach pain [${2}].
3. Easy bruising: The combination of aspirin and Vascepa may increase the likelihood of easy bruising due to their effects on blood clotting [${1}].

It is essential to consult a healthcare professional before combining these medications. They may adjust the dosage or recommend alternative treatments based on individual health conditions and needs.

Sources:
[1] <https://www.drugs.com/drug-interactions/aspirin-with-vascepa-243-0-3407-15790.html>
[2] <https://www.healthline.com/health/drugs/vascepa>
[3] <https://www.drugpatentwatch.com/p/tradename/ASPIRIN>