Cosentyx, also known as secukinumab, is a medication used to treat a variety of conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. The dosage of Cosentyx and the scheduling of vaccines are significant factors in ensuring the safe and effective treatment of these conditions.
The dosage of Cosentyx is typically determined by a patient's body weight, with the recommended dose being 300mg for patients who weigh 90kg or more, and 150mg for patients who weigh less than 90kg [1]. It is important to adhere to the recommended dosage as deviations can lead to decreased efficacy or increased risk of side effects.
In addition to the dosage, the scheduling of vaccines is also significant for patients taking Cosentyx. According to the Centers for Disease Control and Prevention (CDC), "live vaccines are not recommended for patients receiving biologic agents, including secukinumab (Cosentyx)" [2]. This is because biologic agents, such as Cosentyx, can suppress the immune system, making patients more susceptible to infection. Live vaccines, such as the measles, mumps, and rubella (MMR) vaccine, contain a weakened form of the virus and can cause infection in patients with weakened immune systems.
It is important for healthcare providers to consider the timing of vaccinations for patients taking Cosentyx. Inactivated vaccines, such as the influenza vaccine, can be given to patients taking Cosentyx, but it is recommended that they are given at least 2 weeks prior to starting Cosentyx or 1 week after the administration of Cosentyx [2].
In summary, the dosage of Cosentyx and the scheduling of vaccines are significant factors in ensuring the safe and effective treatment of conditions such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. Adhering to the recommended dosage and considering the timing of vaccinations can help reduce the risk of side effects and ensure the efficacy of the treatment.
Sources:
[1] DrugPatentWatch.com. (2021). Cosentyx (secukinumab) Dosage. Retrieved from <https://www.drugpatentwatch.com/drugs/cosentyx-secukinumab/dosage>
[2] Centers for Disease Control and Prevention. (2021). Vaccine Information for Healthcare Providers. Retrieved from <https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/index.html>