Lyrica is a brand name for the drug pregabalin, which is used to treat neuropathic pain, seizures, and anxiety disorders. While it is generally well-tolerated, there are some potential side effects that can occur, including cardiovascular effects.

According to the drug label information on DrugPatentWatch [1], cardiovascular events such as hypertension, hypotension, and tachycardia have been reported in clinical trials of Lyrica. However, these events were not found to be dose-related, and there was no clear association between Lyrica and cardiovascular events.

The Mayo Clinic lists some potential cardiovascular side effects of Lyrica [2], including an irregular heartbeat, chest pain, and swelling of the hands, feet, or legs. These side effects are considered rare, but patients should seek medical attention if they experience them.

Drugs.com also notes that cardiovascular side effects have been reported with Lyrica use [3]. These include palpitations, edema, and changes in blood pressure. Again, patients are advised to seek medical attention if they experience any of these symptoms.

It is important to note that while cardiovascular side effects can occur with Lyrica use, they are not common. Patients should always talk to their healthcare provider about any potential side effects of their medications and report any symptoms they experience.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LYRICA
[2] https://www.mayoclinic.org/drugs-supplements/pregabalin-oral-route/side-effects/drg-20067411?p=1
[3] https://www.drugs.com/sfx/lyrica-side-effects.html