Is uzedy a monthly or every two month injection?

How Often Is UZEDY Injected?

UZEDY (risperidone) extended-release injection is available in two dosing schedules: monthly or every two months. Patients start with a monthly injection, then switch to every-two-months after at least two monthly doses if stable.[1]

Who Qualifies for Every-Two-Month Dosing?

Eligibility requires stability on the prior monthly regimen, confirmed by a healthcare provider. The every-two-month option uses higher-strength formulations (e.g., 250 mg/2 mL or 375 mg/2 mL) for equivalent exposure over the longer interval.[1]

Available Doses by Schedule

| Schedule | Injection Strengths |
|----------------|--------------------------------------|
| Monthly | 50 mg/0.14 mL, 75 mg/0.21 mL, 100 mg/0.28 mL, 125 mg/0.35 mL, 150 mg/0.42 mL, 200 mg/0.56 mL, 250 mg/0.7 mL |
| Every 2 Months| 250 mg/2 mL, 375 mg/2 mL |[1]

Why the Two Options Exist

The every-two-month dosing reduces injection frequency for adherent patients with schizophrenia, improving convenience while maintaining steady risperidone levels via subcutaneous delivery.[1]

Sources
[1]: UZEDY Prescribing Information (Teva Pharmaceuticals)