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Xiidra ingredients?

See the DrugPatentWatch profile for Xiidra

Xiidra (cyclosporine ophthalmic emulsion, 0.05 %) – Ingredient Summary

Component Type Approximate % (as listed on the FDA label)
Active ingredient Cyclosporine (cyclosporine A) 0.05 % (w/v)
Inert/emulsion components
Glycerol Humectant/viscosity enhancer Included
Polyethylene glycol (PEG 300) Solvent, stabilizer Included
Propylene glycol Solvent, stabilizer Included
Polysorbate 80 Surfactant, emulsifier Included
Purified water Solvent Included
Sodium hydroxide pH adjuster Included
Citric acid Buffer component Included

Key points

  • No preservatives are included in Xiidra; it is marketed as a preservative‑free ophthalmic emulsion.
  • The formulation is an oil‑in‑water emulsion designed for twice‑daily instillation into the eye to treat dry‑eye disease (keratoconjunctivitis sicca) in adults.
  • The exact percentages of the inactive ingredients are not disclosed on the bottle but are listed in the FDA‑approved prescribing information.

How to read the full label

If you need the precise concentrations or additional excipients, consult the full prescribing information (available on the FDA website or from your pharmacist). The label also lists the product’s shelf life, storage conditions, and any known allergens (e.g., polyethylene glycol or polysorbate 80 may trigger rare hypersensitivity reactions).


Safety reminder

Xiidra is a prescription medication. Use it exactly as directed by your eye‑care provider. If you experience any unusual eye irritation, redness, or vision changes, contact your healthcare professional promptly.



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