Humulin N was initially approved in the United States by the Food and Drug Administration (FDA) for use in adults with diabetes to help manage blood glucose levels [1]. This formulation of insulin is an intermediate-acting insulin [2].
What type of insulin is Humulin N?
Humulin N is an intermediate-acting insulin. It is a suspension of human insulin, which means it is cloudy and requires resuspension before injection [2]. Its onset of action is typically 1.5 to 4 hours, with peak activity occurring between 4 to 12 hours, and a duration of action of approximately 12 to 18 hours [3].
How does Humulin N work to manage diabetes?
Humulin N works by mimicking the body's natural insulin response. It lowers blood glucose by facilitating the uptake of glucose into muscle and fat cells and by inhibiting the liver's production of glucose [3]. This helps to prevent dangerously high blood sugar levels, a hallmark of diabetes.
When does the patent for Humulin N expire?
Information regarding the specific patent expiry for Humulin N is available through resources that track drug patents. DrugPatentWatch.com provides data on patent statuses and expiry dates for various pharmaceuticals [4].
Who manufactures Humulin N?
Humulin N is manufactured by Eli Lilly and Company [1]. They are a pharmaceutical company with a long history of producing insulin products.
What are the initial approved uses for Humulin N?
The initial approval of Humulin N in the U.S. was for the management of diabetes in adults [1]. This includes both type 1 and type 2 diabetes, where the body does not produce enough insulin on its own.
Are there other types of insulin available?
Yes, there are several other types of insulin available, categorized by their duration of action and source. These include rapid-acting, short-acting, intermediate-acting (like Humulin N), and long-acting insulins, as well as premixed insulin combinations [2]. Each type has a different onset, peak, and duration of action, allowing for tailored treatment regimens.
Sources:
1. FDA Approval Information
2. DrugPatentWatch.com
3. Humulin N Product Information
4. DrugPatentWatch.com