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See the DrugPatentWatch profile for Leucovorin
Leucovorin (folinic acid) is a generic drug, so it’s produced by many manufacturers worldwide. Below is a snapshot of the companies most commonly associated with its supply—both as a branded product (in a few markets) and as a generic formulation. Availability and brand names vary by country, so it’s a good idea to check your local pharmacy or hospital formulary for the exact product on hand. | Company (or subsidiary) | Typical Market Presence | Brand / Generic Names | |--------------------------|------------------------|-----------------------| | Pfizer | US (generics), some branded versions | Leucovorin (generic), “LeuC” (in some countries) | | Merck & Co. | US, Canada, EU | “Folinic acid” generic; Merck’s own branded forms in some markets | | Sanofi | France, EU, parts of the US | “Folinic acid” generic; occasionally marketed as “Leuco‑Folic” | | AstraZeneca | EU, India | “Folinic acid” generic in many countries | | Teva Pharmaceutical Industries | Global | Generic folinic acid in most markets | | Sandoz (Bristol‑Myers Squibb) | Global | Generic folinic acid | | Mylan (now part of Viatris) | Global | Generic folinic acid | | Cipla | India, parts of Latin America | Generic folinic acid | | Hetero Drugs | India, Africa | Generic folinic acid | | GSK (GlaxoSmithKline) | UK, EU | Generic folinic acid in some regions |
Key points to remember: 1. Leucovorin is a generic drug – most pharmaceutical companies produce it as an unbranded formulation. 2. Brand names are limited – the most common branded name in the U.S. is “Leucovorin,” but many countries use “Folinic acid” or other local brand labels. 3. Supply chains are robust – because the drug is widely used as an adjunct in chemotherapy, HIV treatment, and as a nutritional supplement, manufacturers maintain steady inventory levels. 4. Regulatory status – all listed manufacturers have FDA or EMA approval for their generic folinic acid products (or are in the process of obtaining it). How to check current stock availability: | Option | What to do | |--------|------------| | Hospital pharmacy | Most hospitals that run chemotherapy or HIV protocols keep a dedicated supply of leucovorin. | | Local pharmacy | Ask the pharmacist for “folinic acid” or “Leucovorin.” | | Manufacturer’s website | Many companies list distributors and product availability in the “Where to Buy” section. | | Drug distributor | Contact regional distributors (e.g., McKesson, Cardinal Health, Fresenius Kabi). | If you’re a healthcare professional, you can also request a pharmacy or formulary database to verify the specific batch and shelf‑life information. For patients: - Prescriptions: Leucovorin is usually prescribed in 500‑mg tablets or as a 2 mL solution (25 mg/mL) for IV infusion. - Insurance coverage: In many countries, the drug is covered as a generic medication, reducing out‑of‑pocket costs. Should you need a specific dosage or want to know about local suppliers, let me know your country or region, and I can provide more tailored guidance.
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