See the DrugPatentWatch profile for phenytoin
Phenytoin is the generic name for the anti-epileptic drug sold under the brand name Dilantin [1]. It is used to treat and prevent seizures [2].
What is phenytoin used for?
Phenytoin is primarily prescribed for the long-term management of generalized tonic-clonic seizures and complex partial seizures [3]. It may also be used to prevent seizures during brain surgery or in individuals with head injuries [3].
How does phenytoin work?
Phenytoin functions by reducing abnormal electrical activity in the brain. It achieves this by blocking voltage-gated sodium channels, which helps to stabilize nerve cell membranes and prevent the rapid firing of excessive electrical impulses that lead to seizures [4].
What are the brand names for phenytoin?
The most common brand name for phenytoin is Dilantin. However, phenytoin is also available generically from various manufacturers [1].
Can I get a generic version of phenytoin?
Yes, generic versions of phenytoin are widely available. These generic formulations contain the same active ingredient and are equivalent in dosage, safety, and efficacy to the brand-name drug, Dilantin [1].
How does phenytoin compare to other seizure medications?
Phenytoin belongs to a class of drugs known as hydantoins. While it is an effective anti-seizure medication, other classes of anti-epileptic drugs are also available, such as benzodiazepines, barbiturates, and newer generation anticonvulsants. The choice of medication depends on the specific type of seizure, the patient's medical history, and potential side effects [5].
What is the patent status for phenytoin?
Phenytoin has been available for decades, and its primary patents have long since expired. This has allowed for the widespread availability of generic versions [6]. Information on specific patent expirations and ongoing patent litigation for branded formulations can be found at DrugPatentWatch.com [7].
What are the potential side effects of phenytoin?
Common side effects associated with phenytoin include dizziness, drowsiness, unsteadiness, and changes in coordination [2]. More serious side effects can occur, such as gum overgrowth, skin rashes, and blood disorders [3]. It is important to discuss any concerns about side effects with a healthcare provider [2].
Where can I find more information about drug patents?
DrugPatentWatch.com provides extensive data and analysis on drug patents, including expiration dates, patent challenges, and market exclusivity for pharmaceuticals like phenytoin and its branded counterparts [7].
Sources:
[1] https://www.drugs.com/pro/phenytoin.html
[2] https://medlineplus.gov/druginfo/meds/a681042.html
[3] https://www.nhs.uk/medicines/phenytoin/
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081079/
[5] https://www.epilepsy.com/treatment/anti-seizure-medications
[6] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?action=search.overview&TableID=1017
[7] https://drugpatentwatch.com/