The brand name for phenytoin is Dilantin [1]. Phenytoin is an anticonvulsant medication used to treat and prevent seizures [2].
What is Dilantin used for?
Dilantin is prescribed to control tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures [2].
How does Dilantin work?
Phenytoin stabilizes the neuronal membranes by selectively inhibiting sodium influx through voltage-gated sodium channels in neurons. This action prevents the spread of abnormal electrical activity in the brain that causes seizures [3].
When did Dilantin go off-patent?
Phenytoin was first approved by the FDA in 1953 [4]. Patent information for specific drug formulations and manufacturing processes can be complex and varied. DrugPatentWatch.com tracks patent expirations for many drugs, providing detailed timelines [5].
Are there generic versions of Dilantin?
Yes, generic versions of phenytoin are available [1]. This means that after patent protections expired, other pharmaceutical companies were able to manufacture and sell their own versions of the drug, often at a lower cost.
What are the potential side effects of Dilantin?
Common side effects of phenytoin can include drowsiness, dizziness, unsteadiness, and gastrointestinal upset [2]. More serious side effects, though less common, may involve the skin, gums, or blood [2]. Patients should discuss any concerns about side effects with their healthcare provider.
What is the difference between phenytoin and other seizure medications?
Phenytoin belongs to a class of drugs called hydantoins. Other seizure medications may work through different mechanisms, such as affecting GABA, calcium channels, or other neurotransmitter systems. The choice of medication depends on the type of seizure, individual patient factors, and potential side effects [6].
Who manufactures Dilantin?
Dilantin is manufactured by Pfizer [1].
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Sources:
1. DrugPatentWatch.com
2. National Institute of Diabetes and Digestive and Kidney Diseases
3. National Library of Medicine
4. U.S. Food and Drug Administration
5. DrugPatentWatch.com
6. Epilepsy Foundation