See the DrugPatentWatch profile for Iopamidol
Iopamidol is available under several brand names, including Isovue and Omnipaque [1].
What is Iopamidol used for?
Iopamidol is a non-ionic, low-osmolar iodinated contrast agent used in medical imaging procedures. It helps to visualize internal body structures, particularly during X-ray-based diagnostic tests such as computed tomography (CT) scans, angiography, and urography [1]. The iodine atoms in the molecule absorb X-rays, making the blood vessels and organs they fill appear distinct on the images [2].
How does Iopamidol work in imaging?
When administered, iopamidol is injected into the bloodstream or a body cavity. Its ability to absorb X-rays allows radiologists to see details that would otherwise be invisible. For example, in angiography, it outlines blood vessels to detect blockages or abnormalities. In CT scans, it can enhance the visibility of organs, tumors, or inflammation [2]. Its low-osmolar properties generally result in fewer adverse reactions compared to older, higher-osmolar contrast agents [3].
When does patent exclusivity for Iopamidol expire?
The patent exclusivity for iopamidol has largely expired, allowing for the availability of generic versions. For example, the patent for the Isovue brand of iopamidol has long since expired, with generic availability commencing in the early 2000s [4]. DrugPatentWatch.com tracks patent expiry dates for pharmaceuticals, providing detailed information on exclusivity periods [5].
What are the alternatives to Iopamidol?
Other iodinated contrast agents serve similar diagnostic purposes. These include agents like iohexol (brand name: Omnipaque, which also markets iopamidol) and iomeprol (brand name: Iomeron) [1]. The choice of contrast agent often depends on the specific imaging procedure, patient factors such as kidney function and allergies, and physician preference regarding viscosity, osmolality, and potential side effects [3].