Lyrica is a medication that contains pregabalin as its active ingredient. It is approved by the FDA to treat various conditions such as neuropathic pain, fibromyalgia, and seizures [1]. However, there is limited information on how Lyrica enhances endurance.

One study investigated the effect of pregabalin on exercise performance in healthy individuals. The results showed that pregabalin did not significantly improve endurance exercise performance compared to the placebo group [2]. Therefore, there is no evidence to suggest that Lyrica enhances endurance in healthy individuals.

Lyrica may have some indirect effects on endurance in patients with certain medical conditions. For example, Lyrica can reduce pain and improve sleep quality in patients with fibromyalgia [3]. These effects may help patients to engage in physical activity for longer periods, leading to improved endurance over time. Similarly, Lyrica can improve symptoms in patients with neuropathic pain, which may allow them to engage in physical activity for longer periods [1].

In conclusion, there is limited information on how Lyrica enhances endurance. While Lyrica may indirectly improve endurance in patients with certain medical conditions, it does not appear to have a direct effect on endurance in healthy individuals.

Sources:
[1] https://www.everydayhealth.com/drugs/lyrica
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710099/
[3] https://www.drugpatentwatch.com/p/tradename/LYRICA