How Cosentyx Increases Skin Infection Risk
Cosentyx (secukinumab) suppresses IL-17, weakening skin's immune defenses and raising infection risk, including fungal (like candidiasis), bacterial, and cellulitis. Clinical trials showed 1-2% of users developed serious infections, with skin sites most common.[1][2]
Daily Hygiene Practices to Prevent Infections
Wash skin daily with mild soap and lukewarm water, patting dry gently. Moisturize promptly to avoid cracks that invite bacteria. Avoid sharing towels or razors. Trim nails short to reduce scratching injury.[1][3]
What to Avoid Before Injections
Do not inject into red, swollen, bruised, or infected skin. Rotate sites (thigh, abdomen, upper arm) and clean with alcohol swab, letting it dry fully. Use new needles each time.[2][4]
When to Check with Your Doctor
Contact your doctor immediately for signs of infection: redness, warmth, pus, fever over 100.4°F, or swelling at injection sites or elsewhere. Get screened for tuberculosis or hepatitis before starting, as Cosentyx can reactivate latent infections.[1][2]
Vaccination Rules Before and During Treatment
Update live vaccines (e.g., MMR, shingles) at least 4 weeks before starting Cosentyx. Avoid live vaccines while on it. Non-live vaccines (flu, pneumonia) are safe and recommended yearly.[2][3]
Managing Underlying Skin Conditions
If you have psoriasis or eczema, treat flares promptly to limit open skin. Use prescribed topicals alongside Cosentyx. Probiotics or antifungal creams may help if prone to yeast infections, but only under doctor guidance.[1][4]
[1]: Cosentyx Prescribing Information (Novartis)
[2]: FDA Label for Secukinumab
[3]: American Academy of Dermatology Guidelines on Biologics
[4]: Drugs.com Cosentyx Side Effects