How Neffy Is Administered
Neffy (epinephrine nasal spray) delivers emergency treatment for anaphylaxis by spraying a single dose into one nostril. Users remove the dust cap from the device, hold it upright, and insert the tip fully into a nostril while sealing the other nostril by pressing the finger against it. They then press the plunger firmly to release the spray and hold for 5 seconds before removing it. The device activates automatically upon pressure—no priming or shaking needed.[1]
Dosage for Adults and Children
Adults and kids over 30 kg (66 lbs) use one 2 mg spray (10 mg/mL concentration). Children 15-30 kg (33-66 lbs) use one 1 mg spray (2 mg/mL concentration). If symptoms persist after 5 minutes, administer a second dose into the opposite nostril using a new device.[1]
What Happens If the First Dose Doesn't Work
A second dose from a new Neffy device goes in the other nostril. Users should call emergency services immediately after the first dose, regardless. Each prescription includes two devices for this reason.[1]
Proper Storage and Handling
Store Neffy at room temperature (68-77°F or 20-25°C), away from sunlight and freezing. It has a 4-year shelf life from manufacture, longer than many auto-injectors. Discard if exposed to temperatures above 104°F (40°C) or below 32°F (0°C), or if discolored.[1]
How Neffy Compares to EpiPen Administration
Unlike EpiPen's intramuscular thigh injection, Neffy is needle-free and nasal, reducing needle phobia issues. Both provide epinephrine rapidly—Neffy peaks in blood within 10-20 minutes via nasal absorption—but Neffy avoids disposal hassles and is less intimidating for bystanders.[1][2]
[1] Neffy prescribing information, https://neffy.com/
[2] FDA approval summary, https://www.fda.gov/drugs