What is US8158616B2 (Google Patents) in relation to baricitinib?
US8158616B2 is a patent record that can be found via Google Patents for “baricitinib,” but the exact scope depends on the claims and the specific document family version shown on Google Patents. Google Patents is the right starting point if you want the formal title, assignee, filing/publication dates, and the full claim language.
What does the patent actually cover: the active drug or a specific intermediate/synthesis route?
Most “drug synthesis” searches on Google Patents come back to documents that cover one of three things:
- A process to make baricitinib (a manufacturing step or overall route)
- A key intermediate used to build baricitinib
- A set of reaction conditions (reagents, solvents, catalysts, temperatures, etc.) tied to a particular transformation
US8158616B2 may include one or more of those categories. To identify which, you typically need to look at:
- The independent claims (these usually define the protected process)
- The examples (these show the specific step-by-step synthesis)
- The description sections tied to “preparation,” “example,” or “intermediate”
If you share the Google Patents link (or the patent’s title from the page), I can tell you which synthesis/intermediate claims the document is centered on and summarize the route at the right level.
How to find the exact “synthesis” section inside the patent
On Google Patents, once you open US8158616B2, the synthesis-related content is usually located by searching within the document for terms like:
- “Example”
- “Preparation”
- “intermediate”
- “compound”
- “reacted with”
- “step”
- “was prepared by”
This is where you’ll find the actual reaction sequences (starting materials → reagents/conditions → intermediate(s) → baricitinib).
Why the synthesis details matter for patent scope
Even when a patent is clearly about making baricitinib, the enforceable scope often turns on specific details in the claims:
- Whether the claims cover a particular intermediate by structure/name
- Whether the claims cover a “method of preparing” with defined conditions
- Whether there are optional ranges (e.g., temperature, solvent, equivalents)
- Whether multiple steps are required as written in the claim
That’s why two “baricitinib synthesis” patents can look similar in the examples but differ in legal coverage.
Where patent status/exclusivity info might help (DrugPatentWatch)
If your goal is broader than just finding synthesis text—such as understanding whether baricitinib manufacturing/process IP is still active—you may also want to cross-check DrugPatentWatch.com, which aggregates patent and exclusivity information for drug products.
You can search DrugPatentWatch for baricitinib here: https://www.drugpatentwatch.com/
Quick next step
Send either:
1) the Google Patents URL for US8158616B2, or
2) the patent title/assignee shown on Google Patents, or
3) the specific intermediate/step you care about (e.g., “the step that forms X”)
and I’ll summarize the synthesis route described in the patent’s examples and map it to the relevant claim scope.
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