See the DrugPatentWatch profile for Sanctura
What side effects can Sanctura XR cause?
Sanctura XR (trospium chloride extended-release) can cause side effects that are largely related to its anticholinergic (bladder-relaxing) effects. Commonly reported effects include dry mouth, constipation, and blurred vision [1]. People may also experience stomach upset and trouble with urination depending on the person and dose [1].
What are the more serious side effects to watch for?
Seek prompt medical care if you develop signs of an allergic reaction (such as swelling of the face/lips or trouble breathing). Because anticholinergics can affect the whole body, get medical attention if you notice severe constipation, severe abdominal pain, or inability to pass urine, which can happen if bladder or bowel function is overly suppressed [1].
How do side effects differ by sex, age, or other conditions?
The risk of troublesome anticholinergic side effects can be higher in older adults and in people with certain conditions such as constipation/intestinal blockage risk, glaucoma, or urinary retention problems. If you have these issues, your prescriber may choose a different treatment or adjust monitoring closely [1].
Can Sanctura XR worsen constipation or cause urinary retention?
Yes. Trospium can slow gut movement and reduce bladder contractions, which can worsen constipation in some people and can contribute to difficulty emptying the bladder (urinary retention) in others [1]. If you notice worsening constipation or new trouble urinating, contact your clinician.
Does Sanctura XR cause dry mouth?
Dry mouth is a commonly reported side effect of Sanctura XR and other anticholinergic medicines [1]. Staying well hydrated and using sugar-free gum or lozenges may help, but talk with your clinician if it becomes severe.
When do side effects usually start, and what helps?
Side effects often begin soon after starting or increasing the dose and can improve as your body adjusts. If they persist or are bothersome, your prescriber may reduce the dose, adjust timing, or switch therapy [1].
What could increase side effects when taking other medicines?
Other drugs with anticholinergic effects can increase the likelihood of side effects like dry mouth, constipation, blurred vision, and urinary problems [1]. Tell your prescriber about all medications and supplements you take, including over-the-counter cold/allergy products.
What should you do if you miss a dose?
Follow your prescribing instructions. Do not take extra doses to make up for a missed one, since higher-than-intended doses can increase side effects [1].
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Sources:
[1] https://www.rxlist.com/sanctura-xr-drug.htm