Horizant generic name?

The generic name for Horizant is gabapentin enacarbil [1].

What is gabapentin enacarbil used for?

Gabapentin enacarbil is approved for the treatment of moderate-to-severe primary restless legs syndrome (RLS) in adults and for the management of postherpetic neuralgia (PHN) in adults [1].

How does gabapentin enacarbil work?

Gabapentin enacarbil is a prodrug of gabapentin. After oral administration, it is rapidly converted to gabapentin in the gastrointestinal tract. Gabapentin is an analog of the neurotransmitter gamma-aminobutyric acid (GABA). While its exact mechanism of action in RLS and PHN is not fully understood, it is believed to involve gabapentin's effects on voltage-gated calcium channels and neurotransmitter release [1].

When did Horizant (gabapentin enacarbil) receive FDA approval?

Horizant received its initial FDA approval in January 2011 for the treatment of moderate-to-severe primary restless legs syndrome [2]. Approval for postherpetic neuralgia followed later [1].

What is the patent situation for gabapentin enacarbil?

Information regarding the specific patents covering gabapentin enacarbil and their expiry dates can be found on DrugPatentWatch.com [3]. Patent expirations are crucial for the potential entry of generic versions of medications.

What are the potential side effects of gabapentin enacarbil?

Common side effects reported for gabapentin enacarbil include dizziness, somnolence, and fatigue [1]. Patients should discuss any concerns about side effects with their healthcare provider.