How much does lokelma lower potassium?

Lokelma (patiromer) lowers potassium by binding it in the gut and removing it in the stool. In people with high potassium, the average reduction tends to be about 0.5 to 1.0 mEq/L, with many patients around a 0.7 mEq/L drop. The effect is dose‑dependent and builds with continued dosing over days.

Key points:
- Typical starting dose: 8.4 g once daily with a meal.
- Dose can be increased up to 25.2 g per day in divided doses, based on potassium level and tolerance.
- Onset: reductions can be seen within 1–2 days and continue with ongoing treatment.
- Take other oral meds at least 3 hours before or after Lokelma to avoid interactions.
- Monitor magnesium as low magnesium can occur with long‑term use.

If you have a specific potassium level or are considering a dose change, discuss with your clinician for personalized targets and dosing. This is general information and not a substitute for medical advice.