What does it mean if Google Patents shows a histamine-production “US patent application”?
“US patent application” on Google Patents usually refers to a published US filing (for example, “US 20xx/xxxxxxx A1”) rather than an already-issued patent. For histamine production specifically, the matching records could relate to methods, microorganisms/cell engineering, enzymes, or fermentation processes that generate histamine, or to ways to detect/quantify it (because those often live in the same technology space).
How to search Google Patents effectively for histamine production (US applications)
Use keyword combinations that match how patents describe the chemistry and the process. Useful search terms typically include:
- “histamine production”
- “histidine decarboxylase” (the enzyme that produces histamine from histidine)
- “L-histidine decarboxylase”
- “histamine-forming”
- “decarboxylation” + “histidine”
- “bioreactor” or “fermentation” + histamine
- “microorganism” + histamine
- “histamine concentration” (often appears in production or control claims)
Also filter by jurisdiction and document type:
- Set location to United States (US) and use publication numbers like US A1/A2 if you want applications.
- If you see too many irrelevant hits, try adding one technical constraint (enzyme name, organism, fermentation, or “process for producing”).
What kinds of claims show up in patents about producing histamine?
Patent applications about “histamine production” commonly claim one or more of the following:
- A process for producing histamine using an enzyme (often histidine decarboxylase) under defined conditions.
- Engineered microbes or selected strains that convert histidine to histamine during fermentation or bioprocess steps.
- Process parameters that affect yield or reduce unwanted byproducts.
- Purification steps (or formulations) that isolate histamine from a reaction broth.
- Assays or analytical methods related to histamine levels (these sometimes appear alongside production/control technologies).
Is “histamine production” sometimes about making it for medicine vs. reducing it in food?
Yes. “Histamine production” can be searched in two opposite directions in patents:
- Producing histamine (for research, reference standards, or specific applications).
- Preventing or controlling histamine formation (common in food-safety patents, since histamine can form during spoilage). Those documents may mention “histamine formation” or “inhibiting histidine decarboxylase,” which may look related on search results even though the goal is reduction rather than production.
If you want only production (not inhibition), include terms like “produce,” “producing,” “production process,” or “synthesis,” and exclude terms like “inhibit,” “reduction,” “food,” “safety,” if your results are mixed.
How can you tell whether a record is a US application or an issued patent?
On Google Patents, look for the document number format:
- Published application: US 20xx/xxxxxxx A1 (and sometimes A2).
- Issued patent: US x,xxx,xxx B1 (or B2).
A record labeled as an “application” may later grant, but you have to open the document to confirm the status.
Can you share the exact Google Patents link or publication number?
If you paste the Google Patents URL or the US publication number you’re seeing, I can help interpret:
- what the application is actually about (enzyme/microbe/process vs. detection/inhibition),
- the key claims,
- and whether it looks like true “production” or “control” technology.