Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to sources [1][2][3], it is possible for Lipitor to interact with certain supplements, which can lead to adverse effects.

One supplement that can interact with Lipitor is red yeast rice. Red yeast rice contains a substance called monacolin K, which is similar to the active ingredient in Lipitor. Taking both Lipitor and red yeast rice together can increase the risk of muscle pain and damage.

Another supplement that can interact with Lipitor is St. John's wort. St. John's wort is commonly used to treat depression, anxiety, and sleep disorders. However, it can also affect the liver's ability to break down medications, including Lipitor. This can lead to an increase in the level of Lipitor in the blood, which can increase the risk of side effects.

Other supplements that may interact with Lipitor include coenzyme Q10, vitamin D, and fish oil. However, the evidence for these interactions is not as strong as for red yeast rice and St. John's wort.

It is important to talk to a healthcare provider before taking any supplements while on Lipitor. They can provide guidance on which supplements are safe to take and which ones should be avoided. Additionally, it is important to inform the healthcare provider of all medications and supplements being taken to avoid any potential interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/
[3] https://www.singlecare.com/blog/atorvastatin-interactions/