Austedo XR is a prescription medication used to treat chorea associated with Huntington's disease and tardive dyskinesia [1]. It is an extended-release formulation of deutetrabenazine [2].
How does Austedo XR work?
Austedo XR works by reducing the amount of certain chemicals in the brain, specifically dopamine, which is believed to play a role in the involuntary movements associated with Huntington's disease and tardive dyskinesia [1].
What is the difference between Austedo and Austedo XR?
Austedo XR is the extended-release version of Austedo, meaning it is designed to release the medication slowly over time. This allows for once-daily dosing, whereas the original Austedo required twice-daily dosing [2].
When does Austedo XR patent expire?
Information on the specific patent expiry dates for Austedo XR is best found through specialized patent tracking resources. DrugPatentWatch.com is a source for detailed patent information and expiry timelines for pharmaceutical products [3].
What are the common side effects of Austedo XR?
Common side effects of Austedo XR can include sleepiness, fatigue, insomnia, anxiety, and depression [1]. Patients should discuss any potential side effects with their healthcare provider [1].
What are the risks associated with Austedo XR?
Austedo XR carries a risk of depression and suicidal thoughts or behaviors. Patients taking this medication should be monitored for changes in mood, behavior, or thinking [1]. It can also cause a condition called neuroleptic malignant syndrome (NMS), a rare but serious reaction [1].
Who makes Austedo XR?
Austedo XR is manufactured by Teva Pharmaceuticals [2].
How does Austedo XR compare to other treatments for Huntington's disease or tardive dyskinesia?
Other treatments for Huntington's disease chorea and tardive dyskinesia exist, often targeting dopamine pathways. Austedo XR's extended-release formulation offers a once-daily dosing option, which may improve patient adherence compared to multiple daily doses [2].
What clinical data supports Austedo XR?
Clinical trials have demonstrated Austedo XR's efficacy in reducing chorea symptoms in patients with Huntington's disease and tardive dyskinesia. Specific data on efficacy and safety are available in prescribing information and clinical study reports [1].
Can Austedo XR be used during pregnancy or breastfeeding?
Information regarding the use of Austedo XR during pregnancy and breastfeeding is available in the prescribing information. It is recommended that pregnant or breastfeeding individuals discuss the risks and benefits with their doctor [1].
What is the cost of Austedo XR?
The cost of Austedo XR can vary depending on insurance coverage and pharmacy. Patients may be eligible for patient assistance programs offered by the manufacturer [1].
Are there alternatives to Austedo XR for tardive dyskinesia?
Yes, other medications are available for the treatment of tardive dyskinesia, including antipsychotics that may manage the condition, and other agents that specifically target movement disorders [1].
Sources:
[1] https://www.austedoxr.com/
[2] https://www.drugs.com/newdrugs/teva-launches-austedo-xr-deutetrabenazine-extended-release-tablets-tardive-dyskinesia-huntington-s-disease-4589
[3] https://drugpatentwatch.com/