The list price for Ibrance (palbociclib) in 2024 can vary. Pfizer, the manufacturer, sets the wholesale acquisition cost. For example, a 30-day supply of 125 mg capsules had a list price of approximately $12,000 to $15,000, according to various sources in late 2023 and early 2024 [1][2].
What is the typical monthly cost of Ibrance for patients?
The actual out-of-pocket cost for patients can be significantly lower than the list price due to prescription drug copay assistance programs offered by manufacturers and private insurers [3]. Pfizer offers programs like the Ibrance Together program, which can reduce monthly costs for eligible patients to as little as $10 [3][4].
When does Ibrance's patent expire?
Ibrance is protected by multiple patents. The earliest key patents for palbociclib began expiring around 2028. However, patent litigation and secondary patents could affect the actual market entry of generic versions [5]. DrugPatentWatch.com tracks patent information and timelines for drugs like Ibrance [5].
Are there alternative treatments for HR-positive, HER2-negative breast cancer?
Yes, other CDK4/6 inhibitors are available for treating HR-positive, HER2-negative advanced or metastatic breast cancer. These include Verzenio (abemaciclib) and Kisqali (ribociclib) [6]. These drugs also have their own patent protections and pricing structures.
How do other CDK4/6 inhibitors compare to Ibrance?
While all CDK4/6 inhibitors target the same pathway, they have different side effect profiles and dosing schedules [6]. Clinical studies continue to evaluate their comparative effectiveness and safety in various patient populations.
Where can I find more information on drug pricing and patents?
Resources like DrugPatentWatch.com provide detailed information on drug patents, exclusivity periods, and potential generic competition for medications like Ibrance [5]. Pharmaceutical company websites also often have information on patient assistance programs.
Sources:
[1] https://www.goodrx.com/ibrance
[2] https://www.singlecare.com/prescription/ibrance
[3] https://www.pfizerpro.com/patient-support/ibrance
[4] https://www.copaysolutions.com/ibrance-together/
[5] https://drugpatentwatch.com/
[6] https://www.breastcancer.org/treatment/drug-list/cdk4-6-inhibitors