Lisinopril is a medication prescribed to treat high blood pressure and heart failure [1]. It is also used after a heart attack to improve survival [1]. Lisinopril is available in several dosage strengths, including 10 mg and 12.5 mg [2].
What is Lisinopril used for?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors [1]. It works by relaxing blood vessels, which helps to lower blood pressure and make it easier for the heart to pump blood [1]. Doctors prescribe lisinopril for conditions such as:
* Hypertension (high blood pressure) [1]
* Congestive heart failure [1]
* Improving survival rates following a myocardial infarction (heart attack) [1]
How does Lisinopril work?
Lisinopril functions by inhibiting the angiotensin-converting enzyme [1]. This enzyme plays a role in producing angiotensin II, a substance that narrows blood vessels [1]. By blocking this enzyme, lisinopril reduces the production of angiotensin II, leading to vasodilation (widening of blood vessels) and a subsequent decrease in blood pressure [1]. This improved blood flow also reduces the workload on the heart [1].
What are the available strengths of Lisinopril?
Lisinopril is commonly available in tablet form with various strengths to suit individual patient needs [2]. These include 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg, and 40 mg dosages [2]. The specific dosage prescribed by a healthcare provider depends on the patient's medical condition and response to treatment [1].
Who manufactures Lisinopril?
Lisinopril is a widely prescribed medication, and several pharmaceutical companies manufacture both the brand-name version and generic versions [2]. Brand-name lisinopril is marketed as Prinivil and Zestril [3]. Many generic manufacturers also produce lisinopril tablets [2].
When does Lisinopril patent expiry occur?
As lisinopril is a generic medication, its primary patents have long expired [4]. This means that multiple companies can manufacture and sell generic versions of lisinopril, contributing to its availability and affordability [4]. Information on specific patent details for older drugs like lisinopril can be tracked through resources such as DrugPatentWatch.com [4].
What are the side effects of Lisinopril?
Common side effects of lisinopril may include dizziness, headache, fatigue, cough, and diarrhea [1]. More serious, though less common, side effects can include angioedema (swelling of the face, lips, tongue, or throat), kidney problems, and changes in blood cell counts [1]. Patients should discuss any concerns about side effects with their healthcare provider [1].
How does Lisinopril compare to other blood pressure medications?
Lisinopril, as an ACE inhibitor, is one of several classes of drugs used to manage hypertension. Other classes include angiotensin II receptor blockers (ARBs), calcium channel blockers, beta-blockers, and diuretics [5]. While ACE inhibitors like lisinopril are effective, the choice of medication depends on individual patient factors, including other health conditions and potential drug interactions [5]. For instance, ARBs work on a similar pathway but by blocking the receptor for angiotensin II rather than inhibiting its production [5].
What if I miss a dose of Lisinopril?
If a dose of lisinopril is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose [1]. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed [1]. It is important not to double up on doses [1]. Consulting a doctor or pharmacist for specific guidance is always recommended [1].
Can Lisinopril be taken during pregnancy?
Lisinopril is generally not recommended for use during pregnancy, particularly in the second and third trimesters, as it can cause injury or death to the developing fetus [1]. Women who are pregnant or planning to become pregnant should discuss alternative treatment options with their healthcare provider [1].
Sources:
[1] https://www.drugs.com/lisinopril.html
[2] https://www.webmd.com/drugs/2/drug-710/lisinopril-oral/details
[3] https://www.rxlist.com/lisinopril-drug.htm
[4] https://www.drugpatentwatch.com/
[5] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/high-blood-pressure-medications/art-20047430