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See the DrugPatentWatch profile for Hydrocortisone
Short answer: Hydrocortisone itself is an active pharmaceutical ingredient (API). There are several API forms related to hydrocortisone (corticosteroids) that are used in medicines, mainly as esters or salts to improve potency, solubility, or topical delivery. Common hydrocortisone API forms you’ll see: - Hydrocortisone (free base) – the core API used in many topical, oral, and injectable products. - Hydrocortisone acetate – an ester used in topical formulations (creams, ointments). - Hydrocortisone valerate – a topical ester; often used for skin conditions. - Hydrocortisone butyrate – a topical ester; more potent than acetate/valerate. - Hydrocortisone palmitate – a topical ester used in creams/ointments. - Hydrocortisone sodium succinate – a water-soluble salt used for injectable/parenteral administration. - Hydrocortisone sodium phosphate (less common) – another soluble salt form used in some parenteral formulations. Notes: - These esterified or salt forms are all derivatives of hydrocortisone and act as API forms in different dosage forms and routes of administration. - In pharmacology, hydrocortisone is the natural glucocorticoid (cortisol) and serves as the reference steroid in this class. If you’re looking for something specific—e.g., a supplier list, regulatory status in a region, or exact pharmacopoeial specifications (USP/EP) for a particular API form—tell me your region and what you plan to make, and I can tailor the details.
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