Lacosamide is an antiepileptic drug used to treat partial-onset seizures in adults and children over the age of four [3]. The safety of lacosamide during pregnancy is not yet fully established, and the use of lacosamide during pregnancy is only recommended if the potential benefits outweigh the potential risks [2].
According to a study published in the Journal of Epilepsy Research, there is limited information available on the safety of lacosamide during pregnancy. The study suggested that the use of lacosamide during pregnancy may increase the risk of adverse pregnancy outcomes, including congenital malformations and developmental delay [1]. However, the study also noted that the risk of adverse outcomes may be lower than that associated with other antiepileptic drugs [1].
The manufacturer of lacosamide recommends that pregnant women should only use the drug if the potential benefits outweigh the potential risks to the fetus [3]. The manufacturer also advises that pregnant women should be closely monitored for adverse effects, and that the lowest effective dose should be used [3].
In conclusion, the safety of lacosamide during pregnancy is not yet fully established, and the use of lacosamide during pregnancy should only be considered if the potential benefits outweigh the potential risks. Pregnant women should be closely monitored for adverse effects, and the lowest effective dose should be used [2][3].
Sources:
[1] https://pubmed.ncbi.nlm.nih.gov/28385340/
[2] https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[3] https://www.epilepsy.com/medications/lacosamide