Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the body [1]. According to a study published in the Journal of Clinical Lipidology, other citrus juices, such as orange and tangerine juice, do not have a significant effect on the metabolism of atorvastatin [3]. However, grapefruit juice can interact with atorvastatin and increase its concentration in the bloodstream, leading to an increased risk of side effects [2].

The interaction between grapefruit juice and atorvastatin occurs because grapefruit juice contains compounds that inhibit the enzymes responsible for breaking down atorvastatin in the liver. This inhibition leads to an increase in the concentration of atorvastatin in the bloodstream, which can cause side effects such as muscle pain, liver damage, and kidney failure [2].

It is important to note that the interaction between grapefruit juice and atorvastatin is not unique to atorvastatin. Grapefruit juice can also interact with other medications, including some blood pressure medications, antihistamines, and antidepressants [2].

In conclusion, while other citrus juices such as orange and tangerine juice do not have a significant effect on the metabolism of atorvastatin, grapefruit juice can interact with atorvastatin and increase its concentration in the bloodstream, leading to an increased risk of side effects. Patients taking atorvastatin should avoid consuming grapefruit juice and should consult their healthcare provider before consuming any other citrus juices or medications [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/